| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05ff905fdc49089f5f25746eaeb40190 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4453
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4523
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-34 |
| filingDate |
1979-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32cd8e2a0baf08ba89b14653c0f6fe4b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ccd014f0f5101bc951c8f43d27965c9 |
| publicationDate |
1980-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
DD-141834-A5 |
| titleOfInvention |
PROCESS FOR THE PREPARATION OF THIAZOLIDIN-4-ON-ESSIGSAEUREDERIVATEN |
| abstract |
The invention relates to a novel chemically peculiar one-pot process for the preparation of thiazolidine-4-one-acetic acid derivatives of general formula I in which R-j is a lower alkyl group. In the process, the 5-bromo derivatives of corresponding carboxylic acid alkyl esters are first prepared by reaction with elemental bromine in a few polar solvents. The resulting hydrogen bromide cleaves the ester bond at a higher temperature, whereupon the 5 ~ 3rom derivatives of the free acid can be reacted in situ directly with piperidine. - Formula I |
| priorityDate |
1978-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |