| abstract |
The invention relates to a process for the preparation of Prostanderivaten of the general formula I, wherein for example: R ind 1 is the radical OR ind 3 (R ind 3 hydrogen, alkyl, etc.) or NHR ind 4 (R ind 4 = acid radical); B straight-chain or branched alkylene group (2 to 10 C atoms); A CH ind 2 - CH ind 2 -, cis CH = CH group, etc .; W free or functionally modified hydroxymethylene group, etc .; D and E together are direct bond or D is straight or branched alkylene group (1 to 5 C atoms) or E is oxygen or sulfur atom; R ind 2 alkyl, cycloalkyl, etc. R ind 5 free or functionally modified hydroxy group, etc. The compounds according to the invention are valuable drugs because of their antihypertensive effect and their property for inhibiting platelet aggregation. They are characterized by great stability, good specificity and long duration of action. - Formula I - |