| abstract |
A subject-matter of the invention are (phenylmethylene)-2-(alkyl)-1-[ omega -(amino)-alkoxyimino]-cycloalkane derivatives of general formula <CHEM> wherein R represents hydrogen, C1-4 alkyl or hydroxyl, R1 stands for C1-12 alkyl, R2 and R3 independently each represents hydrogen, a C1-12 alkyl group, optionally substituted by hydroxy, or a C2-12 alkenyl group, or R2 and R3 together with the nitrogen atom to which they are attached form a 4- to 7-membered heterocyclic ring, optionally comprising an oxygen, sulfur or a further nitrogen atom, which latter optionally may carry a phenyl, benzyl or C1-4 alkyl substituent, R4 and R5 independently each stands for hydrogen, halogen or a C1-4 alkoxy group, or together represent a 3,4-methylenedioxy group, n is an integer from 2 to 5 and A represents a valency bond or a -CH2-group, as well as stereo and optically active isomers and their mixtures, acid-addition salts and quaternary ammonium derivatives thereof. Furthermore the invention is concerned with a process for preparing these compounds as well as medicaments containing them and the use of them for preparing medicaments, particularly having ulcus and gastric-acid-secretion inhibiting effects. |