http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-58999-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-46 |
| filingDate | 1997-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1befb88ec8ed3a8fe5606b2eca5755f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_701fe2e06dd7c63c8abd535b2ecba427 |
| publicationDate | 2000-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-58999-A3 |
| titleOfInvention | Arylsulfonylamino Hydroxamic Acid Derivatives, Pharmaceutical Composition, Method for inhibiting Matrix Metalloproteinase or Production of Tumor Necrosis Factor and Method of Treatment |
| abstract | Atylsulfonylamino hydroxamic acid derivatives of the formula I wherein η, X, R3, R4 and Q are of particular interest are useful in the treatment of conditions selected from the group consisting of arthritis, cancer, tissue ulceration, macular degeneration, restenosis, periodontal disease, epidermolysis bullosa, scleritis and other diseases characterized by matrix metalloproteinase, AIDS, sepsis, septic shock and other diseases involving tumor necrosis factor (TNF) production. In addition, these compounds are useful in combination therapy with standard non-steroidal anti-inflammatory drugs and analgesics and in combination with cytotoxic agents such as adriamycin, daunomycin, cis-platin, etoposide, taxol, taxotere, and other alkaloids such as vincristine in the treatment of cancer. |
| priorityDate | 1997-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 320.