http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-48598-A3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 |
filingDate | 1998-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c954ed78f30d518714bebef9efebcf0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3897de52d879ceadff80e54df100fcc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50f379507d81fc974a480d9ffc40ece0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a92afb30da9e5a7f17ea3bd6d0b6cfa5 |
publicationDate | 1998-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CZ-48598-A3 |
titleOfInvention | Chromate derivatives, the drug containing them, and their use |
abstract | 4-Sulphonamido-chroman derivatives of formula (I) and their salts are new: R1, R2 = H, CF3, C2F5, C3F7, 1-6C alkyl or phenyl (optionally substituted by 1 or 2 F, Cl, Br, I, CF3, Me, OMe, SONH2 and/or SO2Me); or CR1R2 = 2-10C alkylene; Ra = OH, 1-6C alkanoyloxy or 1-6C alkylsulphonyloxy; Rb = H; or Ra+Rb = bond; R3 = R9-CnH2n(NR11)m- (one CH2 group of CnH2n is optionally replaced by O, S, SO, SO2 or NR10); R9 = H or 3-8C cycloalkyl; n = 0-10; m = 0 or 1; R11 = H or 1-6C alkyl; or R9+R11 = 1-8C alkylene; R10 = H, Me or Et; R4 = R12-CrH2r- (one CH2 of CrH2r is optionally replaced by O, CH=CH, C IDENTICAL C, CO, COO, S, SO, SO2 or NR10); R12 = H, 3-8C cycloalkyl, piperidinyl, pyrrolidino, N-morpholino, N-methyl-piperazino, CF3, C2F5 or C3F7, pyridyl, thienyl, imidazolyl or phenyl (the latter 4 all optionally substituted by 1 or 2 of F, Cl, Br, I, CF3, Me, OMe, SO2NH2, S2Me and NHSO2Me); r = 0-20; R5-R8 = H, F, Cl, Br, I, 1-6C alkyl, 3-8C cycloalkyl, CN, CF3, C2F5, C3F7, N3, NO2, CONR13R14, CO2R15, CsH2s-Y- or phenyl (optionally substituted by 1 or 2 F, Cl, Br, I, CF3, Me, OMe, SO2NH2 and SO2Me); R13, R14 = H or 1-3C alkyl; R15 = H, Me, Et, Ph or -CuH2u-NR13R14; u = 2 or 3; R16 = H, 3-8C cycloalkyl, CO2R15, thienyl, imidazolyl, pyridyl, quinolyl, isoquinolyl, piperidyl, pyrrolidino, morpholino, N-methyl-piperazino, CF3, C2F5, C3F7 or phenyl (optionally substituted by 1 or 2 F, Cl, Br, I, CF3, Me, OMe, SO2NH2 and SO2Me); s = 0-6; Y = S, SO, SO2, CO, SO2NR10, O, NR10 or CONR10; provided that two of R5-R8 are not H. |
priorityDate | 1997-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 155.