| abstract |
The present invention relates to novel propenone oxime ethers, a process for their preparation and the pharmaceutical compositions containing them. …<??>The propenone oxime ethers according to the invention correspond to the formula: …<IMAGE>… in which… Ar and Ar' independently represent an unsubstituted, monosubstituted or polysubstituted phenyl group, a 9-anthryl or naphthyl radical or a pyridyl, thienyl or furyl group,… R1 and R2 independently denote a hydrogen atom, a C1-C4-alkyl group or, together with the nitrogen atom to which they are bonded, a pyrrolidinyl-1, piperidino, morpholino or piperazinyl-1 group,… n = 2 or 3 and… M = H, Cl, Br or a C1-C6-alkyl group. …<??>The invention also relates to the salts of the compounds of formula (I). …<??>These compounds have anti-platelet aggregation properties and are 5HT2 receptor antagonists. |