abstract |
The present invention relates to synthetic steroid derivatives of the general formulanof formula (I) wherein the symbols are as defined abovenin the main claim. These are 5-alpha reductase inhibitorsnand can be used in the form of pharmaceutical compositions,nwhich also form part of the solution to treat disordersncaused by too high a level of said hormone.nThese include, for example, prostate hypertophy, acne, sebaceous and increasednhair in women. The solution also relates to novel intermediatesnuseful in the manufacture of synthetic derivativesnof formula I. |