http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-389698-A3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eccd894c99fea2d1c0c8735872bb2309 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_620ecb9324409347c27e96b6071503ee |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-58 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-46 |
filingDate | 1997-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed36c0340485c21901647aec26ff019e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7496f47b14610f073c8cc40f378031d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_240d9f047d214f38ce20e65cd78e1d55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb863c309a002e974b88bbbb8a2ad58d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_845c5ed34aa88a024dfde787761c2931 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b345616e2c1cda76f13c9a618068eb83 |
publicationDate | 1999-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CZ-389698-A3 |
titleOfInvention | Substituted amidinobenzene derivative and pharmaceutical composition containing it |
abstract | A substituted-amidinobenzene derivative of the following general formula (I) or a salt thereof, and a pharmaceutical composition comprising said derivative or a salt thereof and a pharmaceutically acceptable carrier. <CHEM> (the symbols in the above formula have the following meanings: R<1>: a group which can be converted into an amidino group in vivo; R<2> and R<3>: the same or different and each represents a carboxyl group or a group which can be converted into a carboxyl group in vivo; X<1> and X<2>: the same or different and each represents a lower alkylene group; m: 0, 1 or 2, n: 0 or 1, provided that n = 1 when m = 0. They have GPIIb/IIIa receptor antagonizing activity and are useful as medicines for ameliorating ischemic cardiac disorders, adminicula in cardiosurgery operations or in vascular surgery operations, medicines for ameliorating cerebrovascular disorders, and medicines for ameliorating peripheral artery disorders. In addition, they are useful as a prodrug excellent in peroral absorbability and sustainment of the effect. |
priorityDate | 1996-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 230.