abstract |
A pump-activated liquid spray formulation that is not a propellant-driven aerosol formulation comprising solutions or emulsifiable formulations comprising at least 1.0 mg of cannabinoids per 0.1 ml of liquid spray formulation for buccal delivery, wherein the liquid spray formulation comprises tetrahydrocannabinol (THC) and cannabidiol (CBD) in a predetermined weight ratio, solvent and co-solvent, wherein the solvent is ethanol and the liquid spray formulation is discharged through a spray button and fed through the nozzle such that the aerodynamic diameter of the particles produced is between 15 and 45 micrometers. |