| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2bfe0dd5712b6c431064fd458e6da3d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9309c9191c844ce0ba5a2d0f09b57c92 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-35 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-351 |
| filingDate |
2013-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82f0ff799fc3576ce482aa5a7ab52f3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87c5b91414cb070812a97ba862bc6fc1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24b3eb4ee7946f5c04c27f6ce03c4be9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3271d7695a405c5d06807a6dc802d6b |
| publicationDate |
2016-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CZ-306011-B6 |
| titleOfInvention |
A pharmaceutical composition comprising monensin for the treatment of familial adenomatous polyposis |
| abstract |
The present invention relates to novel biological activities of monensin, an antibiotic isolated from Streptomyces cinnamonensis. Monensin has been identified as an effective inhibitor of the canonical Wnt signaling pathway and has been shown to be active in a number of in vitro and in vivo assays. The invention relates to a pharmaceutical composition comprising monensin or a pharmaceutically acceptable salt thereof for use in the treatment of familial adenomatous polyposis. |
| priorityDate |
2013-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |