| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6572ff5df928fd17340eb2a8cb6d8502 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 |
| filingDate |
2003-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f830e6a1af9639b4d4ae8dfb6080aebb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64c1e44d2a4aabb2a4f1d654d460e607
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7240115990564141d9dc6f0f1ca9bb01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fdcd08c184de339633ae9c65f211c07 |
| publicationDate |
2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CZ-305892-B6 |
| titleOfInvention |
Process for preparing highly pure perindopril and intermediates useful in the synthesis |
| abstract |
The present invention relates to a process for the preparation of 1- {2 (S) - [1 (S) - (ethoxycarbonyl) -butylamino] -propionyl} - (3aS, 7aS) -octahydroindole-2 (S) -carboxylic acid of formula I and its t-butylamine salts of formula I 'without contaminants derivable from dicyclohexylcarbodiimide. The invention also relates to novel intermediates of formula III wherein R is lower alkyl or aryl lower alkyl. The compound of formula I, perindopril, is known as an ACE inhibitor. |
| priorityDate |
2002-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |