abstract |
The present invention relates to benzothiazole substituted cyclobut-3-ene-1,2-dione-3-hydrazones of the formula IV having a substituted 2-hydroxyaryl group of the formulas I and II, or having a 2-N (hetero) aryl group of the formula III-V, and their pharmaceutically acceptable salts. These agents have a cytostatic effect and can be used to prepare therapeutics for the treatment of leukemias and cancer. |