Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
filingDate |
2001-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93fb1712f686887e6c96e38275aac2ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_973ff7ce33b9c5f730a90445e1a94cfb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8dfd4fd1f80b9a06d842af2667a6c03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e09464a433b89ea9bf5043193b34ce0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18a65c1eaf6420215fdbe7055d8bcfd5 |
publicationDate |
2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CZ-304856-B6 |
titleOfInvention |
A method for modifying an endogenous or chromosomal locus |
abstract |
A method for modifying an endogenous gene or a selected chromosomal locus in a non-human eukaryotic cell is described, comprising using bacterial homologous recombination to modify a large cloned genomic fragment larger than 20 kb to create a large specifically targeted vector (LTVEC); use of LTVEC to modify an endogenous gene or chromosomal locus with a large cloned genomic fragment to create a modified allele; and detecting the modified allele to modify the endogenous gene or selected chromosomal locus in the non-human eukaryotic cell. |
priorityDate |
2000-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |