Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97f111dd11492774a1d7a36ad4608433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_980f743ddf12d40aa457287da3d47dba |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 |
filingDate |
2009-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b86776a2ecc4849412080403587e14d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3de4193ef1a5e867a4a3d8fc8c5ad4ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5220e51eb037e46baa27283f35562f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8720fc24ac86ac951e0b8364bdc6f6d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54151da1b4a7327276a9e49848760837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03969c638541a510b5d6f292ee675866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1847fefbe620d89f8bc67a5157e58bf0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7633f4b478311c3a42721b4924397cf0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76d4126e838aae867dc5b024fd977b17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c52bcd811a35a3bac765a28c1ce1a8ae |
publicationDate |
2012-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CZ-303171-B6 |
titleOfInvention |
Use of cholestane derivatives for the manufacture of a medicament for the treatment of cancer and associated angiogenesis |
abstract |
The present invention relates to the use of cholestane derivatives for the manufacture of pharmaceutical compositions for use as antitumor and antiangiogenic drugs, including a method for selectively reducing the viability of tumor cells. It further describes the use of these agents to inhibit angiogenesis by inhibiting the migration and formation of tubule of human endothelial cells. It also includes the use of a composition comprising cholestane derivatives to regulate the adverse effects of tumor growth and angiogenesis in mammalian cells in vitro and in vivo. |
priorityDate |
2009-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |