| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0efa077d881a96aeb1e29b21ef1bbb58 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-20 |
| filingDate |
1999-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c5de1deac8201c4757e6fb663a16030
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd1de02a754662299398b92abbef303c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2363ae9bb08a8a5ba13b52ac8dadbbf5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6edb93a2acf9ee6a9d817b681bee4807
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4ea6396cf5e5407de0c956c203ab22c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95c3e3b2e9c50e17a11df387f17cd6c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4765d2ff2141a91e1b51531b8d2bd610
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70339a89a5475ebf0616ef99c22e9753 |
| publicationDate |
2010-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CZ-301828-B6 |
| titleOfInvention |
A method for preparing 1-substituted 5-or 3-hydroxypyrazole |
| abstract |
Described is a process for preparing 1-substituted 5- and / or 3-hydroxypyrazole of formulas I and II which comprises reacting (a) an alkyl vinyl ether of formula V with phosgene of formula VIa, "diphosgene" of formula VIb or "triphosgene" of formula VIc to form an acyl chloride of formula VII, (b) converting it to the corresponding 3-alkoxyacryloyl chloride of formula VIII by removing hydrogen chloride and (c) esterifying this product with an alcohol of formula IX to give the corresponding alkyl-3-alkoxyacrylate of formula III, and reacting the alkyl-3-alkoxyacrylate of formula III with hydrazine (d) at pH 6 to 11 to give 5-hydroxypyrazole of formula I or (e) at pH 11 to 14 to give 3-hydroxypyrazole of formula II. The meaning of all substituents is given in the description. |
| priorityDate |
1998-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |