abstract |
Extracts of Tanacetum parthenium, containing by weight not more than 0,2% of .alpha.-unsaturated .gamma.-lactone, in particular parthenolide, obtainable by a process of: (a) extracting airborne plant parts with acetone, alcohols or mixtures of these solvents with water; c) the non-hydrocarbon phase is extracted with an apolar solvent, d) to an extract in an apolar solvent, evaporated and redissolved in a mixture of water and alcohol, treated with a strongly basic resin, e) the resin is eluted with alcohols and f) discarding the resulting eluate, f) treating the resin with an alcoholic acid solution or an acidic solution in a mixture of water and alcohol, evaporating the solution and extracting the resulting residue with an apolar solvent, g) evaporating the apolar solvent of step (f) to a residue. added to the residue after evaporation of the hydrocarbon extract of step (b) and to the acetone or alcohol phase, After extraction with an apolar solvent from step (c), (h), the mixture is evaporated and dried. The invention also provides a pharmaceutical composition with analgesic and anti-inflammatory properties containing said extracts. |