| abstract |
Disclosed are novel synthetic analogues of melectin peptide, originally isolated from poison sacs of solitary vermin of Melecta albifrons, prepared by variation of its structural units with the amino acid encoded, the non-encoded amino acid, or the amino acid in the D-configuration. These substances exhibit antimicrobial, antiviral, antifungal, antiparasitic and anticancer activity and are therefore suitable for the manufacture of a medicament for the treatment of microbial, viral, parasitic and fungal diseases and for the treatment of cancers. |