abstract |
The essence of the solution is the detectable pestivirus label, in which the RNase activity exhibited by the glycoprotein E.sup.RNS.n. by deletions and / or mutations of at least one amino acid of said glycoprotein, provided that the amino acid at positions 297 and / or 346 is different from lysine, as shown in FIG. 1 in the case of CSFV strain Alfort or in corresponding positions in other strains, whereas inactivation of RNase activity results in attenuated (attenuated, attenuated) pestivirus. |