| abstract |
A compound which is a carbamate compound of formula I wherein R 1 is the groups of formulas below, R 2, R 3 and p have a specific meaning or a pharmaceutically acceptable salt thereof, except for 3-quinuclidyl-N-Benzyl-N-phenylcarbamate hydrochloride and its R -enantiomer. The pharmaceutically acceptable salt may be a compound represented by formula (II) wherein R 1, R 2, A, m, n and p have a specific meaning, B is hydrogen, C 1 -C 6 alkoxy, C 3 -C 6 cycloalkyl, -COOR 4 or -OOCR 4, wherein R 4 has a specific meaning, or cyano, naphthyl, 5,6,7,8-tetrahydronaphthyl, biphenyl or a group of formula (i) or (ii), and X.sup. means a pharmaceutically acceptable anion of a monovalent or polyvalent acid. Pharmaceutical compositions comprising a compound of formula I or II and the use of these compounds for the manufacture of a medicament for the treatment of a respiratory, urological or gastrointestinal disease or disorder. |