| abstract |
The present invention relates to a composition for the sudden localized release of a selected agent in the gastrointestinal tract of an animal, said composition comprising: a) a core comprising said agent and a core material that swells upon exposure to an aqueous liquid; and b) a coating surrounding said core, wherein said coating has an outer surface, comprises water-insoluble hydrophilic particles embedded in a water-insoluble carrier, said particles forming channels in said coating in the presence of said aqueous liquid leading from said outer surface of said coating to said coating. and which serves to absorb said liquid through said core. |