| abstract |
A controlled release pharmaceutical composition in the form of a tablet comprising (a) a pharmaceutical product, (b) a high amylose starch consisting of 10 to 60% amylopectin and 40 to 90% amylose, and (c) a polysaccharide or polyol, wherein the high amylose starch and the polysaccharide or polyol are covalently crosslinked with a covalent crosslinking agent, and 0.1 to 30 g of crosslinking agent per 100 g of high amylose starch are used. |