| abstract |
The present invention relates to the use of an isolated DNA or RNA molecule encoding either prosaposin or a prosaposin receptor agonist which is a peptide comprising the amino acid sequence set forth in SEQ ID NO: 3, saposin C or a peptide comprising amino acids 18-29 of saposin C, for the preparation of a medicament for the treatment of neurodegenerative or myelinating disorders, as well as a viral vector comprising a DNA or RNA molecule operably encoding a prosaposin receptor agonist. |