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publicationDate 2009-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CZ-300451-B6
titleOfInvention Process for the preparation of salts of 2- [2- (4-dibenzo [b, f] [1,4] thiazepin-11-yl-1-piperazinyl) ethoxy] ethanol (quetiapine) and their purification
abstract Process for preparing salts of 2- [2- (4-dibenzo [b, f] [1,4] thiazepin-11-yl-1-piperazinyl) ethoxy] ethanol (quetiapine) from quetiapine base and the corresponding acid, where the salt is precipitated from a solvent mixture which is either a mixture of toluene and acetone or ethyl acetate, or toluene, water and acetone or ethyl acetate.
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