| abstract |
Described are compounds of formula I wherein R.sup.1.n., R.sup.2.n., R.sup.91.n., R.sup.92.n., R.sup.93.n. , R.sup.94.n., R.sup.95.n., R.sup.96.n., R.sup.97.n., r, sat are as defined in the claims. The compounds of formula I have potent antithrombotic activity and are suitable, for example, for the treatment and prophylaxis of thromboembolic diseases or restenosis. They are reversible inhibitors of factor VIIa, which is a blood clotting enzyme, and can generally be used in diseases in which undesirable factor VIIa activity is present or in the treatment or prevention of diseases in which inhibition of factor VIIa is required. A process for the preparation of the compounds of the formula I and their use, in particular as active ingredients of pharmaceuticals and pharmacological preparations containing them. |