| abstract |
The invention relates to a composition for the prophylaxis of restenosis. Previously known agents for the prophylaxis of restenosis cannot achieve sufficient active compound concentrations in the respective sections of the vascular wall, since higher doses cause undesirable side effects. In the present solution, at least one lipophilic antihyperplastic agent is added to the formulation, showing a partition coefficient between butanol and water. 0.5. The lipophilic active substance is absorbed rapidly and in sufficient quantities into the vascular wall. The preparation may be liquid and capillary-conventional and may contain contrast media, so that the usually desired contrast image transfers the active substance to the vascular wall without additional cost. However, the formulation can also be applied to a catheter. |