http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-299881-B6

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-12
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-12
filingDate 1999-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dae1453a79090fdf1082d8b1b0ea6ecc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5935accf2eeab22ee7a8ba2121dc539b
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publicationDate 2008-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CZ-299881-B6
titleOfInvention Nitrile compound and process for producing a quinoline derivative
abstract The present invention relates to a nitrile compound of formula 1 and to a process for the preparation of a quinoline derivative 3 wherein the aldehyde compound of formula 2 is reacted with 0.5 to 5 moles of diethyl cyanomethylphosphonate per mole of aldehyde compound in a solvent selected from the group consisting of aromatic hydrocarbons, ether solvents and halogenated solvents, in the presence of a base at a temperature ranging from -20 to 80 degC to form a nitrile compound of formula 1, and then reducing the nitrile compound of formula 1 in an aromatic hydrocarbon solvent at a temperature ranging from -50 to 50 degC. with 0.5 to 5 moles of diisobutylaluminum hydride.
priorityDate 1998-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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