| abstract |
Ethanesulfonyl-piperidine derivatives of formula I wherein R.sup.1.n. represents a hydrogen atom or a hydroxy group; R.sup.2.n. represents a hydrogen atom or a methyl group; X is -O- or -CH.sub.2.n.-; and pharmaceutically acceptable acid addition salts thereof. A medicament comprising one or more derivatives of the general formula I and pharmaceutically inert auxiliaries for the treatment of diseases, in particular for the treatment of diseases involving acute forms of neurodegeneration caused, for example, by stroke or brain trauma; chronic forms of neurodegeneration such as Alzeimer disease, Parkinson's disease, Huntington's disease or ALS (amyotropic lateral sclerosis); neurodegeneration associated with bacterial or viral infections; and diseases such as schizophrenia, anxiety, depression and acute or chronic pain. A process for the preparation of these derivatives and their use in the above pharmaceutical applications. |