| abstract |
Pharmaceutical compositions comprising a combination of an anti-angiogenic agent in the form of a vascular endothelial growth factor receptor tyrosine kinase inhibitor and an antihypertensive selected from a calcium channel blocker, an angiotensin II receptor antagonist, an angiotensin converting enzyme inhibitor and a beta beta blocker which can be used to and a vascular permeability reducing effect in a warm-blooded animal such as man. |