| abstract |
Isoindoline Derivatives of Formula I wherein Y is H.sub.2. or = O, R.sup.1.n. and R.sup.2.n. are independently hydrogen or C 1 -C 4 alkyl and R 3 is 3. is a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or a benzyl group, or a substantially chiral pure (S) - isomer thereof, a substantially chiral pure (R) - isomer or acid addition salt, as well as the use of this derivative for the preparation of drugs for reducing unwanted inflammatory cytokine concentrations and treating inflammation of autoimmune diseases in a mammal. |