abstract |
Process for preparing rosiglitazone of formula I by reduction of 5- [4- [2- (N-methyl-N- (2-pyridyl) amino) ethoxy] benzylidene] thiazolidine-2,4-dione of formula II, wherein at least one reduction is carried out a borohydride of the general formula MBH, wherein M is a cation of the series Na, Li, K, Zn and R.sub.4.nN and R is C.sub.1.n-C.sub.5. n-alkyl, catalysed with cobalt salts in the presence of at least one complexing agent and a suitable solvent. |