| abstract |
The topical pharmaceutical composition comprises aciclovir or a pharmaceutically acceptable salt thereof, dimethicone and at least 30% by weight of a water miscible polyhydric alcohol; as a water miscible polyhydric alcohol, it comprises propylene glycol, butane-1,3-diol or diethylene glycol monoethyl ether, wherein dimethicone is present in an amount of 0.1 to 10% by weight, based on the weight of the composition. The invention also comprises the use of said components for the manufacture of a pharmaceutical composition and a process for the manufacture of such composition. |