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filingDate 1997-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2005-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CZ-295226-B6
titleOfInvention A tablet comprising as active ingredient a therapeutically effective amount of galantamine hydrobromide and a process for its preparation
abstract A tablet comprising as active ingredient a therapeutically effective amount of galantamine hydrobromide (1: 1) and a pharmaceutically acceptable carrier comprising a spray-dried mixture of lactose monohydrate and microcrystalline cellulose in a weight ratio of 75:25, such as diluent and crospolyvidone or croscarmellose, as insoluble or poorly soluble crosslinked a polymer that acts as a disintegrant, wherein the carrier does not contain talc as a lubricant. A method of making such a tablet comprising the steps of: (i) dry-mixing the active ingredient, disintegrant and optionally a diluent glidant; (ii) optionally mixing the lubricant with the mixture obtained in step (i); (iii) compressing the mixture obtained in step (i) or (ii) in a dry state into a tablet; and (iv) optionally film-coating the tablet obtained in step (iii)
priorityDate 1996-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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