http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-294842-B6
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8cbc6261d883f27c8339ffb4b4cfeaa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-74 |
| filingDate | 1998-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f32c92e7cdf6ea609c28715e14f55b7 |
| publicationDate | 2005-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-294842-B6 |
| titleOfInvention | Cyanoguanidines, a process for their preparation and use, and pharmaceutical compositions containing them |
| abstract | Cyanoguanidines of formula I or tautomeric forms thereof, wherein the pyridine ring attachment is in the 3 or 4 position and wherein R.sub.1.n. represents one or more substituents which may be the same or different and are selected from the group consisting of hydrogen, halogen, trifluoromethyl, carboxy, C 1-4 alkyl, C 1-4 alkyl. alkoxy or (C 1-4-4-alkoxy) carbonyl, nitro, amino, or cyano, and Q is C 4-8. a divalent hydrocarbon radical, which may be straight, branched, cyclic, saturated or unsaturated, and X represents carbonyl, carbonylamino, aminocarbonyl, oxycarbonyloxy, oxycarbonyl, carbonyloxy, aminocarbonyloxy, oxythiocarbonylamino or oxythiocarbonyloxy; Y is benzylene or phenylene; and R.sub.2.n. represents one or more substituents, which may be the same or different, and are selected from the group consisting of hydrogen, C 1-4 alkyl, hydroxyC 1-4 alkyl, C 1-4 alkyl. 1-4.n.alkoxy, hydroxy, halogen, trifluoromethyl, cyano, carboxamido, sulfamoyl, nitro, amino, carboxy, (C.sub.1-4.n.alkoxy) carbonyl and benzyloxy groups; and pharmaceutically acceptable non-toxic salts and N-oxides thereof. These compounds are useful for the treatment or prophylaxis of diseases characterized by abnormal cell differentiation and / or proliferation, such as psoriasis or cancer. Process for the preparation of these compounds and their use and pharmaceutical preparations containing them |
| priorityDate | 1997-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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