abstract |
Porphyrin derivatives useful in photodynamic therapy of formula 1, 2, 3, 4 optionally bound to a metal ion, in particular a radioisotope, and / or covalently linked chromophore or fluorescent label and / or conjugated form for targeting the desired tissue or organ where each R.sup.1.n. is independently alkyl (1-6C); each n is independently an integer from 0 to 6; is vinyl, -CHOR ', -CHO, -COOR', -CH (OR ') CH.sub.3., -CH (OR') CH.sub.2. (CH 3), CH (NR 1), CH 2 CN, CH 3 CN (CH 3) 3 CH 3 CN; |