| abstract |
Use of a pyridazino [4,5-b] indole-1-acetamide derivative of the Formula I wherein X is halogen, Y is a substituent selected from the group consisting of hydrogen, halogen, hydroxyl, methyl, methoxy and nitro, R .sub.1.n. R 1 represents an alkyl group having from 1 to 4 carbon atoms; independently of one another, represent a hydrogen atom or a (C1-C4) alkyl group or R.sub.2.n. and together with the nitrogen atom to which they are attached form a pyrrolidinyl, piperidinyl or morpholinyl group for the preparation of a medicament for the prevention and treatment of diseases and disorders associated with dysfunction of peripheral benzodiazepine receptors, which is based on wherein the disease or disorder is a degenerative disease of the peripheral nervous system, a disease or disorder of the heart, nephropathy, skin stress, or a tumor or cancer. |