| abstract |
Disclosed are neuroactive steroids of general formula (VI) wherein R.sup.1.n. represents a hydrogen atom, an OH group or NR.sup.2, wherein R.sup.2 is n. and R.sup.3.n. they may independently represent a hydrogen atom or an alkyl group or together form a heterocycle; means a hydrogen atom or a fluorine atom; means a hydrogen atom or a fluorine atom, an OH group or a carboxymethyloxiline, R.sup.6. is a hydrogen atom, a carboxymethyl group, or a methylene carboxylic acid salt, preferably containing an alkali metal, a primary, a secondary, or a tertiary amine; means COCH.sub.3.n. or the group COOR.sup.8, where R.sup.8.n. is hydrogen, sodium, methyl or triethylammonium. The process for the production of these novel neuroactive steroids consists in introducing a fluorine atom at the 3-alpha position. and insomnia, as well as anesthetics |