http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-293592-A3

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00
filingDate 1992-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_816ebdc685139262630469f5d52ebc66
publicationDate 1993-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CZ-293592-A3
titleOfInvention Process of a single-stage preparation of dirithromycin
abstract The disclosure relates to a new process for the synthesis of the macrolide antibiotic dirithromycin in crystalline form. The process is carried out in a single reaction vessel whereby an acetal dissolved in acetonitrile, in the presence of an acid catalyst, is hydrolyzed to the related hemiacetal which then reacts directly with erythromycylamine to form crystalline dirithromycin.
priorityDate 1991-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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