http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-293497-B6

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6844
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6813
filingDate 2001-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a58cbd0e86cecde124128f39afd0865
publicationDate 2004-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CZ-293497-B6
titleOfInvention Method of quantification of minor genetic information in a mixture with majority
abstract The present invention relates to a method of universal in vitro quantification of minority genetic information in admixture with the majority and their application to various conditions such as pregnancy, non-invasive diagnosis of aneuploidy from biological material derived from pregnancy and fetal fraction of pathological mutations or non-physiological events such as progression of traumatic or oncological The process is carried out by simultaneous quantitative detection of two nucleic acid signals related to the measured reference and measured signal status while evaluating their ratio. The number of individual identical detections is increased so that their aggregate statistical evaluation allows the standard deviation of the measurement to fall below the expected difference in values evaluated. stavůŕ
priorityDate 2001-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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