| abstract |
Sulphonylureas useful for treating conditions selected from the group consisting of meningitis and salpingitis, septic shock, multiple intravascular coagulation and / or adult respiratory distress syndrome, acute or chronic inflammation, arthritis, cholangitis, colitis, encephalitis, endocarditis, glomerulonephritis, hepatitis , myocarditis, pancreatitis, pericarditis, reperfusion injury, vasculitis, acute and delayed hypersensitivity, graft rejection and transplant-versus-host disease, autoimmune diseases such as type 1 diabetes mellitus and multiple sclerosis, periodontal diseases, interstitial pulmonary fibrosis, cirrhosis, systemic sclerosis , keloid formation, IL-1 producing tumors such as autocrine growth factor, cachexia, Alzheimer's disease, percussive injury, depression, atherosclerosis, and osteoporosis in mammals, including humans. |