| abstract |
Azole compounds of formula II-A, wherein R 1 is n. is chloro, fluoro, bromo or trifluoromethyl; R.sub.2.n. is hydrogen, chloro, fluoro, bromo or trifluoromethyl; Z is CH or N; R.sub.3, R.sub.4.n. and R < 5 >, which are the same as R < 3 > or C < 5 > alkyl, with the proviso that if one of the groups R.sub.3 is n. or R.sub.4.n. is the atom of water, the species of these groups is r of the type from R.sub.5.n; X is SO or SO2; R.sub.6.n. does C.sub.1.n.-C.sub.5.n. the polyfluoroalkyl group contains at least two fluorine atoms and optionally halogen atoms selected from chlorine and bromine; their pharmaceutically acceptable salts, their method of manufacture and the pharmaceutical compositions containing them for use as a broad spectrum anti-fungal agent. |