abstract |
Pseudopeptide compounds of formula I wherein A is hydrogen, amidine or substituted amidino, R is hydrogen, alkyl, aryl or aralkyl, m is 1 to 5, n is 0 to 6 and p is 1 to 4, wherein B and Z have a number of meanings specified in the specification. These compounds exhibit antithrombotic activity. The invention also includes a pharmaceutical composition for treating or preventing thrombosis comprising an effective amount of the compound. Also included are intermediates useful in the preparation of these compounds |