http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-291337-B6
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d96121abcf63f7c63b0c1e3639db157c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-868 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 |
| filingDate | 1996-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_497c8c66792e853ca0f37b154ca39d43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e562f076421718a2c347915d8e222ef9 |
| publicationDate | 2003-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-291337-B6 |
| titleOfInvention | The mercaptoalkylpeptidyl compound, its use for the manufacture of a composition for the treatment or prevention of a metalloproteinase or TNFalpha-related condition and a pharmaceutical composition comprising it |
| abstract | A mercaptoalkylpeptidyl compound of formula (I) is described wherein R 1 is n. is C 1 -C 6 alkyl or alkyl-SR 6, wherein alkyl is C 1 -C 6 and R 8 is C 9 -C 6. is C 1 -C 4 alkyl; is a hydrogen atom, R.sup.3, is n. is a group of [Alk] .beta.R.sub.6 in which Alk is an alkyl group having 1 to 6 carbon atoms, n is an integer of 0 or 1, and R is an integer of from 6 to 6 carbon atoms. is C 1 -C 6 alkyl or aryl, X is NH, Y is CH, R 5 is n. is a hydrogen atom, R7 is 7. means a hydrogen atom or an alkyl-CO- group in which the alkyl group is a C 1 -C 4 group, and a C 8 -C 8 group group. "C 1 -C 4 alkyl" substituted with a phthalimide or succinimide group, and salts, solvates and hydrates thereof. Further disclosed is the use of the mercaptoalkyl peptidyl compound of formula (I) for the manufacture of a medicament for the treatment or prevention of a metalloproteinase or TNF.alpha. Condition. A pharmaceutical composition for use in therapy comprising the mercaptoalkyl peptidyl compound of formula (I) is also disclosed. |
| priorityDate | 1995-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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