http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-289827-B6
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b831d369e848397cc711a759c214929a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-68 |
| filingDate | 1994-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4dcfd1157d829128da9562c58b94b87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_169727590eef0f269a7bdece46acede3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83dd13c79c430d8cb54ad540d3114a29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f244f80c3e6a3ae5c893eaef6f6f7fbd |
| publicationDate | 2002-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-289827-B6 |
| titleOfInvention | Process for preparing L-isomer of propargyl ammonium chloride derivatives |
| abstract | The process for preparing the L-isomer of the propargyl ammonium chloride derivative of formula (I) wherein Y is a hydrogen atom or a fluorine atom, decomposes the D-tartar of the L-isomer of the amine of formula (II), wherein Y is as defined above; the scanning of the L-isomer of the amine of the formula II in the present invention from a halide set of the general formula V wherein X is a halogen atom and the reaction of the L-isomer of the general formula III wherein Y is as defined above with hydrogen chloride in the organic solvent, the D-tartrate of the L-isomer of the amine mentioned above in general formula (II) can be reacted in an aqueous suspension with ammonium hydroxide or with an alkali metal salt and / or with an ammonium salt. The product is reacted with 1 and 1.5 molar equivalents of the halide of the formula V at temperatures of 0 and 50 degC in a buffer system of pH 8 and 12, which is produced by releasing the salt set, the aqueous layer is separated from the L-isomer of the amine of the general formula II and the L-isomer of the general formula III in the organic layer is extracted with water, with ammonium hydroxide and water and / or with an aqueous solution of salt phosphates of pH 5.5 and 7.5, with the L-isomer of the amine of formula II or with an aqueous layer of selective partition of L. of the formula III, which is distilled to the L-isomer of the salt of formula I, Y is H or F and X is halogen in all of the general formulas. \ t |
| priorityDate | 1994-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.