| abstract |
In the present invention there are disclosed a naphthyl derivative of the general formula I, in which Re1 represents a hydrogen atom, a hydroxy group, an alkoxy group having 1 to 4 carbon atoms, the group of the general formula {-OCOCi6Hi5}, {-OCO(Ci1-6 alkyl)} or {-OSOi2(Ci2-6 alkyl)}, Re2 represents a hydrogen atom, a hydroxy group, an alkoxy group containing 1 to 4 carbon atoms, the group of the general formula {-OCOCi6Hi5}, {-OCO(Ci1-6 alkyl)} or {-OSOi2(Ci2-6 alkyl)}, or a halogen atom, Re3 represents 1-piperidyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidino-, 4-morfolino-, dimethylamino-, diethylamino-, diisopropylamino- or 1-hexamethyleneimino group and n is 2 or 3, and a pharmaceutically acceptable salt. This derivative is an active substance of a pharmaceutical preparation used particularly when treating diseases connected with post-menopausal syndrome, uterus tumor disease, endometriosis and aortal cell proliferation of saponaceous musculature. In the present invention there are also described processes of its preparation and intermediates used therefor. |