| abstract |
The benzylpiperidine derivative represented by the general formula (I), wherein R is 1. H or halogen; optionally substituted benzyl at the 2, 3 or 4 position of the piperidine ring with halogen in the aromatic moiety; does not denote 4-benzyl when X is -CO-, Y and Z-CH 2. H, R.sup.3.n. H or A, X -CO-, Y-CH 2, -, -NH- or -O-, Z is -CH.sub.2- or bond, A C.sub.1 -16n alkyl and BO, H + OH, Hal F, Cl, Br or J, and salts and isomers thereof are active agents for the treatment of ischemia and for the treatment of neurodegenerative diseases including cerebral vascular diseases. |