http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-287969-B6
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f00b503b4045fc858275a7c77e27c087 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-38 |
| filingDate | 1995-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0621bb25b68d743888544752db94408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51ca06cc232dc8cd5faa57eba808c460 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d160a89ef903f8c94ea6aaada442ee58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d5582af766bfe336cdc892277e71bd9 |
| publicationDate | 2001-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-287969-B6 |
| titleOfInvention | An amidine derivative, a process for its preparation, a pharmaceutical composition comprising the same and its use |
| abstract | An amidine derivative of the Formula I wherein D is a five membered heterocyclic aromatic ring containing from 1 to 4 heteroatoms selected from O, N or S, optionally substituted on carbon by halogen, trifluoromethyl, alkyl of 1 to 6 carbon atoms, nitro or cyano, and is attached to the remainder of the compound of Formula I via a carbon atom; A represents N (X) or CH ((- CH.sub.2.), Sub.multidot.NXY); U represents NH, O or CH.sub.2; V represents (CH.sub.2.) Sub. W represents (CH.sub.2.) Subb. a, b, m, X and Y have specific meanings. Process for the preparation and pharmaceutical compositions containing these derivatives. The amidine derivatives of formula (I) are inhibitors of NO-synthase and are useful in therapy, in particular for the treatment of neurodegenerative diseases, migraine and the like. |
| priorityDate | 1995-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 320.