| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J73-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F3-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H04N5-7458 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H04N5-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J73-00 |
| filingDate |
1993-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4a3190e54d6e76d73d3033ef485b757
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab3abb03ad1b1794d69758ea41cd290c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70d1135cc945f95219edac506b0c9870 |
| publicationDate |
2001-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CZ-287842-B6 |
| titleOfInvention |
Process for preparing 17beta-(N-tert-butylcarbonyl)-4-aza-5alph-androst-1-en-3-one |
| abstract |
In the present invention there is disclosed a process for preparing 17beta-(N-tert-butylcarbonyl)-4-aza-5alpha-androst-1-en-3-one of the general formula 2. The invented preparation process is characterized in that (1) ester of the general formula 1, in which R represents alkyl with linear, branched or cyclic chain and containing 1 to 10 carbon atoms, being either unsubstituted or substituted with at least one phenyl radical is brought into contact with tert-butylaminomagnesium halide, whereby molar ratio of the tert-butylaminomagnesium halide to said ester is at least 2:1, in an inert organic solvent and in inert atmosphere, (2) the obtained reaction mixture temperature is maintained at a temperature of at least 10 degC and (3) the resulting butylcarbonyl of the general formula 2 is then isolated. |
| priorityDate |
1992-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |