Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32898f78b0822968df172655dc75d3 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-66 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42 |
filingDate |
1998-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a4d3672feb263eaf06dfa85367c8aac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_326f32814f68424a60e42fc3c1c88af7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0aae85fc76ae3fae4e72fd618d5365a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46e07d8d9bc980703b1571e2f3ba43bb |
publicationDate |
2001-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CZ-287668-B6 |
titleOfInvention |
New mutant strain of Aspergillus terreus and method of fermentation of lovastatin |
abstract |
Conventional mutagenesis procedures have been developed to obtain a new strain of Aspergillus terreus CCM 8236. The process of aerobic fermentation of lovastatin by Aspergillus terreus strain CCM 8236 in acid form in a laboratory scale submerged culture is described. Inoculum preparation takes place in low pH soil. As a carbon source, a mixture of glucose and lactose (1:22 ratio) is used in the production soil at high concentration and as a nitrogen source for Pharmamedia. On such a soil, the strain produces more than 2000 mg / L of lovastatin in 170 hours |
priorityDate |
1998-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |