Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6895 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1252 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate |
1998-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c31c4ae4180646984bf45db2505c3270 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf211b0e73ff9694e53aa5a55297fc4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d025366d24d38f253b10d60b91b9c6b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01b36f74c1ee687a6773f139013ee050 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a51ba4abead1cd1ba47f08065c70ed76 |
publicationDate |
1999-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CZ-287498-A3 |
titleOfInvention |
Recombinant, thermostable DNA polymerase, a method for its preparation, and a kit containing it |
abstract |
Modified thermostable DNA polymerases having enhanced efficiency for incorporating unconventional nucleotides such as those labeled with fluorescein family dyes are provided. Such modified thermostable DNA polymerases can be prepared by methods of the recombinant DNA technology. Recombinant thermostable DNA polymerases prepared in accordance with the present invention are advantageous in many in vitro DNA synthesis applications, such as DNA sequencing, synthesis of labeled DNA and the production of labeled primer extension products. The said polymerase enzymes are particularly useful in chain termination nucleic acid sequencing methods. Nucleic acids encoding the recombinant thermostable DNA polymerases of the present invention, as well as vectors and host cells comprising same are also provided. Kits comprising the recombinant thermostable DNA polymerases of the present invention are provided too. The polymerases and methods of the present invention provide significant cost and efficiency advantages for DNA sequencing. |
priorityDate |
1997-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |