http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-287326-B6
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37555e87c88017b74fba94c8b8abbb42 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 |
| filingDate | 1996-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e3743cb897dec3ee603a86fc8be2c17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_159291a4bd4694fee159bba692f0299b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed5049420083c9dc6fbf84d90975d9ce |
| publicationDate | 2000-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-287326-B6 |
| titleOfInvention | Taxoids, process of their preparation and pharmaceutical composition in which the taxoids are comprised |
| abstract | In the present invention there are disclosed taxoids of the general formula I, in which Z represents a hydrogen atom or the group of the general formula II, in which Ri1 represents benzoyl or the group Ri2-O-CO-, wherein Ri2 represents alkyl, Ri3 represents phenyl, Ri4 represents alkanoyloxy, alkenoyloxy, cycloalkanoyloxy, cycloalkenoyloxy, benzoyloxy or heterocyclylcarbonyloxy and Ri5 represents an optionally substituted alkoxy. Those taxoids can be prepared for instance by reacting the compounds of the general formulae III and IV. Taxoids of the general formula I, in which Z represents the group of the general formula II, exhibit remarkable antitumor and anti-leukemic activity. In the present invention there is also described a pharmaceutical composition containing as active substance the above specified taxoids. |
| priorityDate | 1995-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.